Therapy of Morbus Parkinson and radical-induced neurotoxicity in the rat--in vivo voltammetric studies.

نویسنده

  • W Wesemann
چکیده

In vivo pulse voltammetry was used to study the effect of anti-parkinsonian drugs and of neurotoxins in rat striatum. It could be demonstrated that besides the well-known changes of total dopamine (DA) concentrations the applied drugs affected also the extraneuronal DA metabolism in the living rat. In addition, neurotoxin-treated rats can be used as a model to study some aspects of the Parkinson syndrome.

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عنوان ژورنال:
  • Journal of neural transmission. Supplementum

دوره 38  شماره 

صفحات  -

تاریخ انتشار 1992